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This astrocyte-neuron lactate shuttle is crucial for maintaining neuronal energy homeostasis when mitochondrial function is impaired (Suzuki et al., 2011

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MSCs could reduce the production of inflammatory factors such as IL, TGF, TNF and interferon (IFN), inhibit the proliferation of T and B cells, reduce IgG secretion, inhibit the maturation of dendritic cell and regulate the activities of other immune cells such as natural killer cells and macrophages (214)